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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24209581cc4541f4c41b2bcd6934cb8e81d61408c7f5763b1fc06ad75e3428a4' 
  AND token = 'gFN9UO+G19vsX+0xrg8WrqhMTXDEcGmT3M9iIn62lJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}