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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd547c2a7b737e5d80fb7678a95df3c016aa7887298a206b075aaf94a1484046d' 
  AND token = 'KRu/ZLeR3hI8thaLS3x1sXA3HVqtcB8YmKabpUnztU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}