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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0eaae15d3d34a24e6e936722fd11ba2f7a12c056c992c0bd94aab5389e6b8f1' 
  AND token = 'eDyGBs78y7iy6n/2iAq0aUlCoKlu7i1VsSk7N77nLCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}