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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0de68bf47537630cea008a5f53bb1c1c88245d6d5919b0f499d57f5bc21849' 
  AND token = 'FVK+wk7eqGsb6erbJY5+bGjO1BssO87DZ6Y4hAkX5LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}