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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4677d6f4770427d0a2cd24a0c0982200ab3bef99642d073ad0103b1334000c6' 
  AND token = 'kh/VKG8VVhw8Imnw1dLMZtt78uuQinfRz67N1UFGnGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}