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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14c4de7492b1e0e53713e370de7daa7ad2c2420a9c20bd21270ea3f42217517' 
  AND token = '/bfTTPipJvZU0pdpKzBL+12a0YQxYrDIMarI9PwzcU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}