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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f10a6afd0e748773acda57decb6b14c3b2008ea59694dee17d9ab94847767177' 
  AND token = 'Cc2qx+7/JlfuhAnPESojz881vL3Idj6gOHmFUfAU6tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}