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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50d405f29865451c27abbe7cb2b946e67d8bf84deba79f60b414d8e908cbeb1' 
  AND token = 'yiLhKJaigZXX9yDNfsVJtEIQwDzAEuTj2vviu9UYxmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}