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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e73030a9b4f5038c9bdfb482b758d0d670f65cd52a8b2ea9b08f766d356b5009' 
  AND token = 'Wc0H9IQZ0C5IPlDhqXHE+L9ZUCUu8g0cNrhNrUJTiis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}