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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80009c21d2ef8c756c9521a186aff497b6ebb2b49b82e73c16e0fda619ca9380' 
  AND token = 'ByBEE52s90QVsWzfzmlN3wQy3R3uzzWUK2JYlmulUZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}