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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05208c1987786c9b336fa74fbfaefa7397cb0b021f6fe8a7e76e3e3c0cd0770a' 
  AND token = 'KoULL4sFXFTugcTDRRSAcCiA7HtaVUHHuW1qVkm0WUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}