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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f2e0cfb1e148c5aff7116fe498261424c90cb9b5f82ae4427dfeab4539fd781' 
  AND token = 'mpjY4Fn1pCp04weUaIRw/+ynuRHEACsoLCpH9nl/ZDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}