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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fea99a9c427964c66e26abf76f5c1bb75398a16f63f30706643268348a8bf916' 
  AND token = '4SRQY0sR4UNyN4bRclEh9Zt2bImTYj256HfzJqIOzmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}