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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218e6a9fda7f17cf8bba5e657ec889e5db50666f54ad41f9d18b8a9f1a092bc9' 
  AND token = 'RJtmGfMcH6XZSk0YRFXM+ahjYpUnWNoT9N+nCPsrwKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}