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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c11ae0caa0d1ba60d913932e7274dc8da3196f4233fc7c984f8d8e3d78635e7d' 
  AND token = 'GFTA/tPOXCBVdpDNDczVADi/QkJ9CMHBjzFJR8skVY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}