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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78fcb7ba1aa97bce9bdc0ab17ac4cca881a41228ce4637b9384bcf7812b913f5' 
  AND token = 'Q5YzJGI7ygxVJTQG7Fv14taoe2t2jr4KcurTzOLv35Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}