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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8829cac5dd9905c1c4ce330f7eee6be4d2a7eb7d10c41811da82862384c99364' 
  AND token = 'c0i1uAex1stxUNfbhODxuza7xhD325YDCYXWW4aqD14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}