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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53675a200811ad75e95b09bd037115fd2badb1c647793431f9610df4fd8e5f90' 
  AND token = 'odeWcpeB0QuKT1Yu5OUz8DBOpIet1z0A228I3JxyL80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}