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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c822764869c343d3189d461b6fd8f7b280615fd296133e83bb03dd03c29a3fd2' 
  AND token = '0gXQ+XMXLzX0xqcFCmjBUd2qR90BB/0VDcspl1/2dBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}