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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381dbecde595425c0aec1e5e2ba908281d02537c001ee83673642714555e033b' 
  AND token = 'YMFq9J4zFA49qjnp+hyutI/5QExMzp9Ol1u4cuZ9BE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}