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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f397e7076f1c1061478057cc53c67d1c28694001a0b00473bf64937cabbba82a' 
  AND token = 'mzkYvEO4VueKNB82HRH1Xwl3F8C+0NJ4sfgZRIV3lTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}