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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730dad5cc45f21346b0153e9c11664bfca29111a35e08104b78a2eff7e18aa9b' 
  AND token = 'rWNY/pp6+ukaUJ9vc/a9UKkFxI8R46c3zCmPkDuDkSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}