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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f59b90c3346133abccb519d9b9593552b09c6b541fb3ff2b7928a2f9bd237e3f' 
  AND token = 'w6B9VTPhu9cK2NZhBe8B99OBQrYdQHezKF4uW2uGXNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}