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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6b2e93efc13da07bccddd5484137382940e30b7a9b55dc7182c1fcc0ade1208' 
  AND token = '7QX2Og/7tkl3wBA0lMr5syyFr4XCTY058vF69P5yfVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}