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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6fcae64c1a7957d9c927ad9793792359e6c47b7ad0cba485a533a4ec9007e3' 
  AND token = 'XE26QlCfsTcizHjiO9UeWHB2Xzrcz2VTbToAuC277EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}