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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ef633d7ea247ac490533e1fab6a52dcd1d917a53637b1d6fdaf9457a5680816' 
  AND token = 'lO3nPTPC50JOrkyaaX6YUFc3zJ9Bxc2ODiXE3b3wLmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}