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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a39c2af993e797e3b96f98b2b2786b0bc6a5e48469e5e627a421ad2331970b' 
  AND token = 'mOL1iUGqQlo+z67uqsNbnT7B5BR6EQjV8FSde2Kp1Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}