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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cac61b85ca673b3c8379b99eee46fba9bf02ec3e1b9215efc08f55a53d079db1' 
  AND token = 'RWkmUF1+tdpkwuOYU6AETu/0LL1iLI0DXvwEvOHnNZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}