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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306644b46ace0b65bb19bbd42562e67695b5cbe8a4d16e121196c34f2df740a5' 
  AND token = 'PJOXU8Bqejae38O0Ut7PbYdmIhLcJf9BJ+2AmiKWX5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}