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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18c81d30a3c7b3ce7c806d504ada8765c7d9bb9acf72d94c6e617e49632f666c' 
  AND token = 'WX5aBPIJ6/mjCoArgxZXcY9ayeRd0ud1v4QsmtL0iac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}