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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '608ce0d6afba0064e39dea8843ea9d3b11dae039b8e34a38c46f9c75a0763692' 
  AND token = 'gyYCmztkeG062T4K6sdN6V0z0yVV+WMHyqqjQ86PHw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}