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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50958b8237d7a42307a74726f414f7f43a7519c9cbd12d7247adbdb672f45c15' 
  AND token = 'oi+XXDpEvidBLux1eLGnLX651MgChh/j//D+ZLa0RTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}