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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0312a70f6412b2560c43609827aa4b746686ec6838b4af80216422095345bf49' 
  AND token = 'QLQDUxrgqBFTaUbMWyTCIjwTUjyiN96+DbDjMZfCVTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}