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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a0f54ff8390abf57bad1b9ea63737e21dea465b2d0bcd452f055c631dfe79d' 
  AND token = 'GD1PP9YJ2nsvZb71ZcS9vMSZRexvn2TVEIKP2lzpia8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}