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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8abde0745d9553b1600897da462495e9ff61398a1800011a3c8951d364e8900' 
  AND token = '3nSIxyd1cmxrVqMpr46nYDlKjWlwlg7wqUjqLS/ILxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}