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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd823342382db18d33e755141f207ca732a657b9e3dbc262577978ab55b58bd09' 
  AND token = 'iXT8moQD7OE3eRRA6GhMnh6dg+4tVsbtnAdScCW86G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}