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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '436eefb731b8da3448fc2b92225eb5c5b8cd753af35dc8393cc0cd1afabcf497' 
  AND token = 'ulsF/3FypfWDK+7yu5xX/KRzaNmaJnI4RPG664vN9cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}