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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '320a48a8a4655b23eadd56064e7fc247c9b67160497e108a84c0aaf914b6c744' 
  AND token = 'e4JHnN2giXdAimETOTzwAwd3zmj13joEoHysTBVunY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}