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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bbb15b6219d803c49bc474bc3775122766dc907e1c5623947e44a71c5f249be' 
  AND token = 's25VmJMe8a7mPfwYN8t289reo4HiV/bBfPQ3i4iH/IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}