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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3414eedfb7919086fce81577c0f6be23725509a8c49e182ee30be52ece93a4f4' 
  AND token = 'MMK/M8m4iLIQcNbYnUXAB53jO/5Om1Fa8aMWZy40gu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}