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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4865126fb675f894c1563e48c5ff49ddd4425d1a7ffa13f8981171822b77dc' 
  AND token = 'z7D4ev9PZPc7jQTs5i84/E3ggR7hS1TC1QaHUjXQOZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}