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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ecf18ec96fdc6aea2e9bbb71e1abc2601c55fc0c9543de11092a1a314701542' 
  AND token = 'tF+Si4Pkh3r44evefbLVkeeEoqeuvwk9NHh2ZUv+fM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}