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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a61fdcc09446a8f279e5ed216db5e887ac3eee86e0270131367b005234f36c' 
  AND token = 'D2uljnDQtwOJ+3/YfPBtkEKqaQwNPH+unyBdqWQZo2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}