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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b07f263d6c1638e51b96a4ba01795519a67b9de6baba72946738809ac16b7be6' 
  AND token = 'dc/c9XcZ+N0jNlQo2yQnguc1RPBTinylq9vtJTYJ/0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}