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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dc89d5024c711aff67c2f438273045c8fca5c30af1d4709ec05e995b068a0dd' 
  AND token = 'J3z7r9kTExth34wtwP1vwBwnMn4iQOfXFFkUQDHtSuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}