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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5037f9190a51434bde5357bfd3479c8304d4ab934692e7c56b549875e6b0a6f' 
  AND token = 'DpoamMk5Tzo4JaQFfhGg1zl5/2dtGuhOU2LI5HelBJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}