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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b888f19ce9239e9706b34945677699388b9d9f8656c1def22c1401c76711fe9' 
  AND token = 'd/mMIn4vrJx/wyrGRzFkz1x4HP30SYy3UvJmnsnnmms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}