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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90f43d25f2fcb5beb93a1b01f9e46c617ccf19c1bceed7c9abc406ee9343b360' 
  AND token = 'AQdJcDPvtLSyc0q6xfknGwpKuT1zsqnW2YE9ZiJmz18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}