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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bbc77b05f5845a160e74abb14f2b0a3e5c0e59a8329685a9e1466a0502039a8' 
  AND token = 'LNNJkeBTHBqVcT11Z3q5dWdfE92ILNHuCnpBwQBwb9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}