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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8381acc9236efaf7bea65ba587761de018a0ece795e3493ba0269f2435b87b7' 
  AND token = 'oPgfcBAg/zVovRNsrbmjlzd+bvnv9nusQyn07gIjM2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}